99mTc-labelled PSMA ligand for radio-guided surgery in nodal metastatic prostate cancer: proof of principle
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چکیده
منابع مشابه
Direct comparison of 99mTc-PSMA SPECT/CT and 68Ga-PSMA PET/CT in patients with prostate cancer
Objective(s): 99mTc-PSMA SPECT/CT is a cost effective alternative for 68Ga-PSMA PET/CT. The aim of this study was to directly compare these two techniques in patients with prostate cancer. Methods: 28 man with prostate cancer were studied using 99mTc-PSMA SPECT/CT and 68Ga-PSMA PET/CT in a shor...
متن کاملThe Iranian Society of Nuclear Medicine practical guideline on radioligand therapy in metastatic castration-resistant prostate cancer using 177Lu-PSMA
Prostate-specific membrane antigen (PSMA) is a type II transmembrane protein, which is anchored in the cell membrane of prostate epithelial cells. It is highly expressed on prostate epithelial cells and strongly up-regulated in prostate cancer. Although, 177Lu-PSMA has been recently introduced for radionuclide therapy of metastatic castration-resistant prostate cancer (mCRPC) with co...
متن کامل225Ac-PSMA-617 for PSMA-Targeted a-Radiation Therapy of Metastatic Castration-Resistant Prostate Cancer
Prostate-specific membrane antigen (PSMA) is a promising target in prostate cancer. Recently, we started the first-in-human treatment with an α-radionuclide–labeled PSMA ligand. Although the case series is still ongoing, we here report in advance about two patients in highly challenging clinical situations who showed a complete response to 225AcPSMA-617 therapy. Methods: 68Ga-PSMA-11 PET/CT val...
متن کامل225Ac-PSMA-617 for PSMA-Targeted α-Radiation Therapy of Metastatic Castration-Resistant Prostate Cancer.
Prostate-specific membrane antigen (PSMA) is a promising target in prostate cancer. Recently, we started the first-in-human treatment with an α-radionuclide-labeled PSMA ligand. Although the case series is still ongoing, we here report in advance about two patients in highly challenging clinical situations who showed a complete response to 225Ac-PSMA-617 therapy. METHODS 68Ga-PSMA-11 PET/CT v...
متن کاملGa-Labelled PSMA Ligand for Prostate Cancer Diagnosis ADDITIONAL ROLE FOR ABIRATERONE IN BLOCKING TUMOUR GROWTH IN CASTRATION RESISTANT PROSTATE CANCER
As part of an EU-supported IMIPREDECT consortium, a Dutch study showed that abiraterone acetate (AA) may have an additional mechanism of action to block growth of castration resistant prostate cancer (CRPC). The study, which won the first prize for best oncology abstract at the 28th European Association of Urology (EAU) Congress, showed that antiandrogenic properties of AA may stop androgen rec...
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ژورنال
عنوان ژورنال: EJNMMI Research
سال: 2021
ISSN: 2191-219X
DOI: 10.1186/s13550-021-00762-1